Direct interaction of fibrinogen with lipid microparticles modulates clotting kinetics and clot structure
D Faizullin, Y Valiullina, V Salnikov, Y Zuev - … Nanotechnology, Biology and …, 2020 - Elsevier
Extensive studies revealed the role of blood lipid microparticles (liposomes, microvesicles)
in activation of coagulation cascade. The direct interaction of fibrinogen/fibrin with lipid
surfaces and its consequence for hemostasis received much less attention. We observed
pronounced changes in both clot morphology and kinetics of fibrin clotting in the presence of
artificial liposomes. The evidence was obtained that lipid microparticles per se present a
diffusion barrier to the three-dimensional fibril assembling and pose spatial restrictions for …
in activation of coagulation cascade. The direct interaction of fibrinogen/fibrin with lipid
surfaces and its consequence for hemostasis received much less attention. We observed
pronounced changes in both clot morphology and kinetics of fibrin clotting in the presence of
artificial liposomes. The evidence was obtained that lipid microparticles per se present a
diffusion barrier to the three-dimensional fibril assembling and pose spatial restrictions for …
Direct interaction of fibrinogen with lipid microparticles modulates clotting kinetics and clot structure
Y Zuev, D Faizullin, Y Valiullina, V Salnikov - dspace.kpfu.ru
© 2019 Elsevier Inc. Extensive studies revealed the role of blood lipid microparticles
(liposomes, microvesicles) in activation of coagulation cascade. The direct interaction of
fibrinogen/fibrin with lipid surfaces and its consequence for hemostasis received much less
attention. We observed pronounced changes in both clot morphology and kinetics of fibrin
clotting in the presence of artificial liposomes. The evidence was obtained that lipid
microparticles per se present a diffusion barrier to the three-dimensional fibril assembling …
(liposomes, microvesicles) in activation of coagulation cascade. The direct interaction of
fibrinogen/fibrin with lipid surfaces and its consequence for hemostasis received much less
attention. We observed pronounced changes in both clot morphology and kinetics of fibrin
clotting in the presence of artificial liposomes. The evidence was obtained that lipid
microparticles per se present a diffusion barrier to the three-dimensional fibril assembling …
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